A SINGLE-DOMAIN ANTIBODY TARGETING COMPLEMENT COMPONENT C5 ACTS AS A SELECTIVE INHIBITOR OF THE TERMINAL PATHWAY OF THE COMPLEMENT SYSTEM AND THUS FUNCTIONALLY MIMICKS THE C-TERMINAL DOMAIN OF THE STAPHYLOCOCCUS AUREUS SSL7 PROTEIN

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

The complement system is an efficient anti-microbial effector mechanism.On the other hand abnormal complement activation is involved in the pathogenesis of multiple inflammatory and hemolytic diseases.As general inhibition of the complement system may jeopardize patient health due to increased susceptibility to infections, the development of pathwa

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Sick-listed employees with severe medically unexplained physical symptoms: burden or routine for the occupational health physician? A cross sectional study

Abstract Background The two primary objectives of this study were to the assess consultation load of occupational health physicians (OHPs), and their difficulties and needs with regard to their sickness certification tasks silver lining herbs kidney support in sick-listed employees with severe medical unexplained physical symptoms (MUPS).Third obje

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Extracts of Knoxia roxburghii (Spreng.) M. A. Rau Induce Apoptosis in Human MCF-7 Breast Cancer Cells via Mitochondrial Pathways

Knoxia roxburghii (Spreng.) M.A.Rau (KR) is a plant clinically used in traditional Chinese medicine (TCM) for the treatment of cancer.The study objectives were to examine the effects of KR extracts, petroleum ether (PET), ethyl acetate (EtoAc), butanol (n-BuOH), and H2O-soluble fractions (HSF) of the 75% EtOH extraction on A549 (non-small cell lung

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